16S Ribosomal RNA Methylation: Emerging Resistance Mechanism against Aminoglycosides
نویسندگان
چکیده
منابع مشابه
16S rRNA Methyltransferases: An Emerging Resistance Mechanism Against Aminoglycosides in Salmonella
Infections with non-typhoidal Salmonella are the second most common cause of bacterial gastroenteritis in developed countries, with the incidence of multidrug-resistant non-typhoidal Salmonella increasing considerably in the last two decades. Non-typhoidal salmonellosis in otherwise healthy individuals usually results in mild, self-limiting diarrhoea, but treatment with an appropriate antimicro...
متن کاملThe 16S ribosomal RNA mutation database (16SMDB)
The 16S ribosomal RNA mutation database (16SMDB) provides a list of mutated positions in 16S ribosomal RNA from Escherichia coli and the identity of each alteration. Information provided for each mutation includes: (i) a brief description of the phenotype(s) associated with each mutation; (ii) whether a mutant phenotype has been detected by in vivo or in vitro methods; (iii) relevant literature...
متن کاملAptazyme-mediated regulation of 16S ribosomal RNA.
Developing artificial genetic switches in order to control gene expression via an external stimulus is an important aim in chemical and synthetic biology. Here, we expand the application range of RNA switches to the regulation of 16S rRNA function in Escherichia coli. For this purpose, we incorporated hammerhead ribozymes at several positions into orthogonalized 16S rRNA. We observed that ribos...
متن کاملLocation of ribosomal protein binding sites on 16S ribosomal RNA.
The distribution of ribosomal protein binding sites on the 16S ribosomal RNA molecule has been analyzed by limited ribonuclease hydrolysis of RNA-protein complexes, as well as by the interaction of individual proteins with RNA fragments purified from partial enzymatic digests. Of the six 30S subunit proteins known to interact directly with 16S RNA, proteins S4, S8, S15, S20, and, probably, S13 ...
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7 Doi Y, Arakawa Y. 16S ribosomal RNA methylation: emerging resistance mechanism against aminoglycosides. Clin Infect Dis 2007; 45: 88–94. 8 Bogaerts P, Galimand M, Bauraing C et al. Emergence of ArmA and RmtB aminoglycoside resistance 16S rRNA methylases in Belgium. J Antimicrob Chemother 2007; 59: 459–64. 9 Wachino J, Shibayama K, Kurokawa H et al. Novel plasmid-mediated 16S rRNA m1A1408 meth...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2007
ISSN: 1058-4838,1537-6591
DOI: 10.1086/518605